Acetazolamide Impurity 1(Acetazolamide EP Impurity A) - Names and Identifiers
Name | N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide
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Synonyms | NSC 231656 Acetazolamide EP Impurity A 2-AMino-5-acetaMido-1,3,4-thiadiazole 2-AcetaMido-5-chloro-1,3,4-thiadiazole 2-(AcetylaMino)-5-chloro-1,3,4-thiadiazole N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetaMide N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide Acetamide,N-(5-chloro-1,3,4-thiadiazol-2-yl)- Acetazolamide Impurity 1(Acetazolamide EP Impurity A)
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CAS | 60320-32-3
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Acetazolamide Impurity 1(Acetazolamide EP Impurity A) - Physico-chemical Properties
Molecular Formula | C4H4ClN3OS
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Molar Mass | 177.61 |
Density | 1.608±0.06 g/cm3(Predicted) |
Melting Point | 245-246 °C(Solv: ethanol (64-17-5)) |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White to Off-White |
pKa | 8.95±0.50(Predicted) |
Storage Condition | Amber Vial, Refrigerator, Under inert atmosphere |
Stability | Light Sensitive |
Acetazolamide Impurity 1(Acetazolamide EP Impurity A) - Introduction
N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide(N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide) is an organic compound whose chemical structure contains a thiadiazole ring and an acetamide group. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide is white crystalline or crystalline powder.
-Solubility: It has low solubility in water and better solubility in organic solvents.
-Melting point: The melting point of N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide is about 130-134 degrees Celsius.
-Stability: It is relatively stable at room temperature, but may decompose or change under the action of light, heat, acid or alkali.
Use:
N-(5-choro-1, 3,4-thiadiazol-2-yl)acetamide has a wide range of uses in the agricultural field, mainly as a fungicide and herbicide. It can effectively control fungi and weeds on some crops.
Preparation Method:
N-(5-choro-1, 3,4-thiadiazol-2-yl)acetamide can be obtained by chemical synthesis. A common synthetic method is to first take 5-Chloro-1,3,4-thiadiazole and then react with acetyl chloride to produce N-(5-Chloro-1,3,4-thiadiazol-2-yl)acetamide.
Safety Information:
- N-(5-choro-1, 3,4-thiadiazol-2-yl)acetamide is relatively low toxic to humans under standard operating conditions. However, it is still a chemical substance and proper safe handling and storage methods should be followed.
-Wear appropriate personal protective equipment such as lab gloves, protective glasses and protective clothing when using or handling N-(5-choro-1, 3,4-thiadiazol-2-yl)acetamide.
-This compound should be kept away from fire and oxidizing agents, and stored in a dry, well-ventilated place, avoiding contact with strong acids, strong bases and high temperatures.
-When disposing of waste, follow local laws and regulations and adopt appropriate treatment and disposal methods.
Last Update:2024-04-09 20:45:29